USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P19105 USC-OGP 2-DE database:  P19105 P19105 General information about the entry View entry in simple text format Entry name ML12A_HUMAN Primary accession number P19105 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;. Gene name Name=MYL12A Synonyms=MLCB, MRLC3, RLC Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0231: pI=4.58; Mw=19347 SPOT OGP-0233: pI=4.62; Mw=19153 SPOT OGP-0235: pI=4.66; Mw=19089 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1315: pI=4.59; Mw=20102 SPOT OGP-1320: pI=4.70; Mw=19395 SPOT OGP-1321: pI=5.74; Mw=19265 Cross-references UniProtKB/Swiss-Prot P19105; ML12A_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ML12A_HUMAN Primary accession number P19105 Secondary accession number(s) Q53X45 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  February 15, 2017 (version 164) Name and origin of the protein Description RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3; Gene name Name=MYL12A Synonyms=MLCB, MRLC3, RLC Encoded on Name=MYL12A; Synonyms=MLCB, MRLC3, RLC Keywords Calcium; Complete proteome; Metal-binding; Motor protein; Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X54304; CAA38201.1; -; mRNA EMBL D82059; BAB88919.1; -; mRNA EMBL EU794621; ACJ13675.1; -; mRNA EMBL AK291145; BAF83834.1; -; mRNA EMBL CH471113; EAX01678.1; -; Genomic_DNA EMBL CH471113; EAX01680.1; -; Genomic_DNA EMBL CH471113; EAX01681.1; -; Genomic_DNA EMBL BC016372; AAH16372.1; -; mRNA EMBL BC031972; AAH31972.1; -; mRNA EMBL BC032748; AAH32748.1; -; mRNA CCDS CCDS11830.1; -; . PIR S11493; MOHULP; . RefSeq NP_001289976.1; NM_001303047.1; . RefSeq NP_001289977.1; NM_001303048.1; . RefSeq NP_001289978.1; NM_001303049.1; . RefSeq NP_006462.1; NM_006471.3; . UniGene Hs.190086; -; . ProteinModelPortal P19105; -; . SMR P19105; -; . BioGrid 115871; 50; . IntAct P19105; 32; . MINT MINT-1159148; -; . STRING 9606.ENSP00000217652; -; . iPTMnet P19105; -; . PhosphoSitePlus P19105; -; . SwissPalm P19105; -; . BioMuta MYL12A; -; . DMDM 127169; -; . OGP P19105; -; . SWISS-2DPAGE P19105; -; . EPD P19105; -; . PaxDb P19105; -; . PeptideAtlas P19105; -; . PRIDE P19105; -; . TopDownProteomics P19105; -; . DNASU 10627; -; . Ensembl ENST00000217652; ENSP00000217652; ENSG00000101608; . Ensembl ENST00000536605; ENSP00000441231; ENSG00000101608; . Ensembl ENST00000578611; ENSP00000463614; ENSG00000101608; . Ensembl ENST00000579226; ENSP00000462171; ENSG00000101608; . GeneID 10627; -; . KEGG hsa:10627; -; . UCSC uc002klr.3; human; . CTD 10627; -; . DisGeNET 10627; -; . GeneCards MYL12A; -; . HGNC HGNC:16701; MYL12A; . HPA CAB004503; -; . HPA HPA039262; -; . HPA HPA045244; -; . HPA HPA059197; -; . MIM 609211; gene; . neXtProt NX_P19105; -; . OpenTargets ENSG00000101608; -; . PharmGKB PA164723273; -; . eggNOG KOG0031; Eukaryota; . eggNOG COG5126; LUCA; . GeneTree ENSGT00760000119196; -; . HOGENOM HOG000233018; -; . InParanoid P19105; -; . KO K12757; -; . PhylomeDB P19105; -; . TreeFam TF314218; -; . Reactome R-HSA-3928664; Ephrin signaling; . Reactome R-HSA-445355; Smooth Muscle Contraction; . ChiTaRS MYL12A; human; . GeneWiki MRCL3; -; . GenomeRNAi 10627; -; . PRO PR:P19105; -; . Proteomes UP000005640; Chromosome 18; . Bgee ENSG00000101608; -; . ExpressionAtlas P19105; baseline and differential; . Genevisible P19105; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016459; C:myosin complex; IEA:UniProtKB-KW; . GO GO:0005509; F:calcium ion binding; IEA:InterPro; . GO GO:0048013; P:ephrin receptor signaling pathway; TAS:Reactome; . GO GO:0006936; P:muscle contraction; TAS:Reactome; . GO GO:0070527; P:platelet aggregation; IMP:UniProtKB; . CDD cd00051; EFh; 1; . Gene3D 1.10.238.10; -; 2; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR015070; EF_hand_DJBP; . InterPro IPR002048; EF_hand_dom; . Pfam PF08976; EF-hand_11; 1; . Pfam PF13499; EF-hand_7; 1; . SMART SM00054; EFh; 2; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 3; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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